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Gzms participate in the process of pyroptosis and immunology. Gzms are released by CTLs. Gzm‐A cleaves GSDMD to induce pyroptosis. Gzm‐B activates caspase‐4/‐5/‐11 to cleave GSDMD. Gzm‐B can activate or directly cleave GSDME to induce pyroptosis
