TABLE 2.

Correlation analysis between the plasma miR21‐5p level and various clinical parameters

	Age	BMI	WBC	RBC	Plt	PT‐INR	BUN/Cre	AST	ALT	Alb	CRP	CEA	CA19‐9
(a) Preoperative value at 1 mo post‐operation
P‐value	.02*	.95	.27	<.001***	.98	.78	.76	.14	.84	.98	.28	.44	.19
Correlation coefficient(ρ)a	0.22	0.01	0.11	−0.33	−0.003	−0.03	−0.03	0.14	0.02	0.002	0.11	0.08	0.13
(b) Postoperative value at 1 mo post‐operation
P‐value	.12	.93	.29	<.001***	.07	.21	.27	.29	.58	.06	.06	.80	.81
Correlation coefficient(ρ)b	0.15	−0.01	0.11	−0.34	0.18	0.18	−0.11	0.11	0.05	−0.19	0.18	−0.02	0.02
(c) Postoperative value at 6 mo post‐operation
P‐value	.11	.10	.89	.08	.69	.17	.42	.34	.45	.13	.31	.15	.61
Correlation coefficient(ρ)c	0.16	−0.17	0.01	−0.18	−0.04	0.24	−0.08	0.10	−0.08	−0.16	0.11	0.15	−0.05

*P < .05; **P < .01; ***P < .001.

^a Spearman's rank correlation coefficient with preoperative plasma miR21‐5p level.

^b Spearman's rank correlation coefficient with postoperative plasma miR21‐5p level at postoperative 1 mo.

^c Spearman's rank correlation coefficient with postoperative change in plasma miR21 level at postoperative 6 mo.