FIGURE 1.

Astragalus polysaccharides (APS) attenuate the immunosuppressive activity of myeloid‐derived suppressor cells (MDSC) in melanoma mice. Mice were given APS (200 mg/kg/d) or normal saline (Model) after tumor inoculation. A, The tumor weight of mice from APS and Model groups. B, Image of tumor blocks. C‐E, Changes of myeloid cells, including dendritic cells (DC) (C), macrophages (D), and MDSC (E) in the spleen of mice in the APS group compared with the Model group. F, Bar chart of DC, macrophages, and MDSC content in the spleen. (G), The expression of Arg‐1, IL‐10, TGF‐β was quantified by qRT‐PCR. All these data were presented as mean ± SD. *P < .05, **P < .01, ***P < .001