FIGURE 5.

Silent information regulator 2 (SIRT2) regulated the expression of apoptosis‐related factors in clear cell renal cell carcinoma cells. A, B, Expression of Bax and Bcl2 in stably transfected ACHN, 786‐O, Caki‐1, and relevant control cells were detected by (A) quantitative real‐time PCR and (B) western blot analysis. Bars represent means ± SD from three independent experiments, each carried out in triplicate. *P < .05, **P < .01 vs corresponding controls (unpaired‐sample Student’s t test). KD, knockdown; OE, overexpression