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. 2021 Aug 10;112(10):4176–4186. doi: 10.1111/cas.15089

FIGURE 5.

FIGURE 5

POU4F2 activates the Hedgehog pathway in vitro and in vivo. A, The association between POU4F2 and the Hedgehog pathway in gene set enrichment analysis. B, Protein expression of the Hedgehog pathway in HCT116 cells with or without a POU4F2 knock‐down. C, Protein expression of the Hedgehog pathway in RKO cells with or without a POU4F2 knock‐down. D, Protein expression of the Hedgehog pathway in lung metastatic nodes for each mouse. All experiments were performed in triplicate. Data are presented as the mean ± SEM (**P < .01, ***P < .001, ****P < .0001)