Table 2.
Odds ratios for prediction of long-term survival (dependent variable) associated with FACT-O-TOI at different treatment time points (adjusted for age, stage, grade, performance status, residual disease, treatment, and baseline FACT-O-TOI)
| Dependent variable | STS, No. | LTS, No. | OR (95% CI) | SE | Pa | Increase in adjusted OR for LTS with 7 pt increase in FACT-O-TOI |
|---|---|---|---|---|---|---|
| TOI at pre-cycle 4 | 863 | 225 | 1.01 (1.00 to 1.03) | 0.01 | .04 | 1.10 |
| TOI at pre-cycle 7 | 832 | 219 | 1.01 (1.00 to 1.02) | 0.01 | .27 | 1.05 |
| TOI at pre-cycle 13 | 729 | 215 | 1.03 (1.02 to 1.04) | 0.01 | <.001 | 1.22 |
| TOI at pre-cycle 21 | 614 | 215 | 1.05 (1.04 to 1.07) | 0.01 | <.001 | 1.40 |
| TOI at 6 mo post treatment | 510 | 209 | 1.06 (1.04 to 1.07) | 0.01 | <.001 | 1.45 |
a
Data tested using 2-sided z-test. CI = confidence interval; FACT-O-TOI = Functional Assessment of Cancer Therapy–Ovary Trial Outcome Index; LTS = long-term survivor; OR = odds ratio; SE = standard error; STS = short-term survivor; TOI = Trial Outcome Index.