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. 2021 May 10;47(6):1091–1107. doi: 10.1590/S1677-5538.IBJU.2021.99.12

Table 1. Antimuscarinic agents for adults with OAB.

Starting dose regimen* Dose escalation*
Darifenacin 7.5mg 15mg
Fesoterodine 4mg 8mg
Imidafenacin 0.1mg bid 0.2mg bid
Oxybutynin** 10mg ER or 5mg IR bid or tid 115-20mg ER or 5mg qid
Propiverine** 30mg ER or 15mg IR bid 45mg ER or 15mg IR tid
Solifenacin 5mg 10mg
Tolterodine 4mg ER or 2mg IR bid Not evaluated
Trospium 60mg ER or 20mg bid Not evaluated
*

Recommended initial dose for adults with no liver or renal function impairment; Unless noted, regimens are once-daily dosing; bid: twice a day; tid: three times a day; IR: immediate release; ER: extended release;

**

Agents with mixed mechanism of action but predominant antimuscarinic action.