Table 3.
Characteristics | Total, no. | Effective, no. (%) | P | |
---|---|---|---|---|
Sex | Male | 15 | 9 (60) | 0.323 |
Female | 18 | 7 (38.89) | ||
| ||||
Age | <55 years | 17 | 8 (47.06) | 0.971 |
≥55 years | 16 | 8 (50) | ||
| ||||
ECOG | 0 | 10 | 8 (80) | 0.034 |
1 | 23 | 8 (34.78) | ||
| ||||
Primary tumor location | Left | 23 | 9 (39.13) | 0.164 |
Right | 10 | 7 (70) | ||
| ||||
Liver metastases | Yes | 20 | 10 (50) | 0.782 |
No | 13 | 6 (46.15) | ||
| ||||
Lung metastases | Yes | 28 | 11 (39.29) | 0.032 |
No | 5 | 5 (100) | ||
| ||||
Lymph node metastasis | Yes | 22 | 12 (54.55) | 0.286 |
No | 11 | 4 (36.36) | ||
| ||||
Excision of primary lesion | Yes | 29 | 15 (51.72) | 0.181 |
No | 4 | 1 (25) | ||
| ||||
Raltitrexed | Yes | 12 | 4 (33.33) | 0.2 |
No | 21 | 12 (57.14) | ||
| ||||
Bevacizumab | Yes | 28 | 11 (39.29) | 0.034 |
No | 5 | 5 (100) | ||
| ||||
Cetuximab | Yes | 11 | 4 (6.36) | 0.101 |
No | 22 | 12 (54.55) | ||
| ||||
Number of previous chemotherapy lines | 2 line | 16 | 12 (75) | 0.005 |
3 lines or above | 17 | 4 (23.53) | ||
| ||||
Regorafenib | 80 mg | 23 | 10 (43.48) | 0.456 |
120 mg | 10 | 6 (60) | ||
| ||||
KRAS | Mutation | 8 | 5 (62.5) | 0.203 |
Wild | 13 | 4 (30.77) |
ECOG, Eastern Cooperative Oncology Group performance status.