Table 3.
The association between total bilirubin concentrations and mean telomere length by sex.
| Total bilirubin, mg/dL | Male (n = 3767) | Female (n = 4051) | Total (n = 7818) | |||
|---|---|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | β (95% CI) | P value | |
| Crude model | ||||||
| Q1 | Ref | Ref | Ref | |||
| Q2 | 0.01 (-0.01, 0.03) | 0.567 | 0.02 (-0.00, 0.04) | 0.118 | 0.02 (-0.00, 0.04) | 0.131 |
| Q3 | 0.03 (0.01, 0.05) | 0.112 | 0.05 (0.03, 0.07) | <0.001 | 0.04 (0.02, 0.06) | <0.001 |
| Q4 | 0.04 (0.01, 0.07) | 0.017 | 0.03 (0.00, 0.05) | 0.022 | 0.04 (0.02, 0.05) | <0.001 |
| Q5 | 0.06 (0.02, 0.09) | <0.001 | 0.03 (0.00, 0.06) | 0.048 | 0.05 (0.03, 0.07) | <0.001 |
| P for trend | <0.001 | 0.002 | <0.001 | |||
| Adjusted model∗ | ||||||
| Q1 | Ref | Ref | Ref | |||
| Q2 | 0.01 (-0.02, 0.05) | 0.457 | 0.03 (0.01, 0.05) | 0.015 | 0.03 (0.01, 0.04) | 0.008 |
| Q3 | 0.03 (-0.01, 0.06) | 0.122 | 0.06 (0.04, 0.08) | <0.001 | 0.05 (0.03, 0.07) | <0.001 |
| Q4 | 0.03 (0.00, 0.06) | 0.042 | 0.05 (0.03, 0.07) | <0.001 | 0.05 (0.03, 0.06) | <0.001 |
| Q5 | 0.04 (0.00, 0.07) | 0.024 | 0.04 (0.02, 0.07) | 0.002 | 0.05 (0.03, 0.07) | <0.001 |
| P for trend | 0.013 | <0.001 | <0.001 | |||
∗Adjusted model adjust for age (continuous), race (non-Hispanic white, black, Mexican American, other Hispanic, other race/ethnicity or missing), education (less than high school, high school, more than high school, or missing), body mass index (<18.5, 18.5- <25, 25- <30, ≥30, or missing), smoke status (none, past, current, or missing), alcohol (yes, no, or missing), physical activity (no aerobic activity, low activity, moderate activity, high activity, or missing), energy intake (Q1-Q4), diabetes (yes, no, or missing), hypertension (yes, no, or missing), and C-reactive protein (Q1-Q3).