Fig. 6.

Osteoclast parameters are elevated in mice infected with SARS-CoV-2. A) Representative micrographs of TRAP staining in femurs from non-infected (n = 8) and infected mice (n = 7). Osteoclasts stain red (red arrows). Quantitation of B) Number of osteoclasts (N.Oc); C) number of osteoclasts per bone surface (N.Oc/BS); D) osteoclast surface (Oc.S); and E) osteoclast surface per bone surface (Oc.S/BS). *p < 0.05 or ***p < 0.005 compared to non-infected mice. Statistical analysis was performed using a Student's t-test. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)