Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

. 2021 Oct 2;47(11):1181–1247. doi: 10.1007/s00134-021-06506-y

Recommendations
22. For adults with sepsis or septic shock at high risk of fungal infection, we suggest using empiric antifungal therapy over no antifungal therapy Weak recommendation, low quality of evidence
23. For adults with sepsis or septic shock at low risk of fungal infection, we suggest against empiric use of antifungal therapy Weak recommendation, low quality of evidence

Recommendations

22. For adults with sepsis or septic shock at high risk of fungal infection, we suggest using empiric antifungal therapy over no antifungal therapy

Weak recommendation, low quality of evidence

23. For adults with sepsis or septic shock at low risk of fungal infection, we suggest against empiric use of antifungal therapy

Weak recommendation, low quality of evidence