Table 3.

Multivariate analysis in relapse cohort for overall survival, progression-free survival, and relapse.

	Overall survival				Progression-free survival				Relapse
Risk Factor	N	N-event	HR (95% CI)	p	N	N-event	HR (95% CI)	p	N	N-event	HR (95% CI)	p
Total					99	87			99	70
Patient gender
Male	65	49			59	49			59	39
Female	45	36	0.66 (0.41–1.08)	0.1021	40	38	1.13 (0.71–1.79)	0.6049	40	31	1.21 (0.72–2.01)	0.4689
Donor type
Other	53	43			44	38			44	28
HLA-HLA	57	42	0.4 (0.24–0.67)	<0.001	55	49	0.53 (0.31–0.91)	0.0219	55	42	0.7 (0.39–1.27)	0.2373
Disease stage
Low	51	39			45	38			45	26
Advanced	59	46	0.94 (0.58–1.53)	0.8145	54	49	1.28 (0.79–2.07)	0.3216	54	44	1.85 (1.05–3.24)	0.0327
Conditioning
Standard	52	42			45	40			45	32
Reduced	58	43	0.85 (0.55–1.32)	0.4654	54	47	1.03 (0.66–1.59)	0.9093	54	38	1.09 (0.67–1.79)	0.7297
Previous GvHD
No previous GvHD	52	43			46	44			46	37
Any previous GvHD	58	42	0.68 (0.42–1.1)	0.1165	53	43	0.71 (0.44–1.15)	0.1614	53	33	0.66 (0.38–1.14)	0.1338
Age (decades)	110	85	1.22 (0.89–1.68)	0.2055	99	87	1.09 (0.79–1.51)	0.5831	99	70	1.28 (0.88–1.86)	0.2013
Interval to T x 2	110	85	0.98 (0.9–1.07)	0.6776	99	87	0.94 (0.86–1.03)	0.1945	99	70	0.88 (0.79–0.98)	0.0186

Bold values indicate statistical significance p < 0.05.