Table 1.
Treatment | Mechanism Target | Clinical benefit? | Mortality decrease? |
---|---|---|---|
Remdesivir | RNA-dependent RNA polymerase | ✓ | ✓/Mixed |
Favipiravir | RNA-dependent RNA polymerase | ✓ | X |
Lopinavir/Ritonavir | Viral protease | ✓ | X |
Peginterferon λ-1a | General viral replication, cell activity | Mixed | X |
✓ - The drug produced the respective column’s effect. X - The drug failed to produce the respective column’s effect. Mixed - The drug produced negative and positive outcomes or only produced positive outcomes in some trials. * - Clinical trials of this drug either failed to exceed 100 participants or lacked any blinding.