Table 2.
Clinical data and outcome measures reported by studies.
| Author (year) | Treatment (n) | Device (n) | Outcomes | Complications (n) |
|---|---|---|---|---|
| Manrique-Huarte21 (2018) | Unreported | Unreported | PTA, WRS, VHIT, VMP | None reported |
| Canzi13 (2017) | IT Gent (4) | Unreported | HIT, PTA, Open-set SRS, THI, MD-FLS, DHI, MDPOSI | None reported |
| Mukherjee24 (2017) | CI w/o Lab (22), CI + Lab(6), CI + Lab delayed (3) |
CN: CI512 (5) | PTA, BKB, CUNY | Bilateral vestibular failure, oscillopsia, vertigo (1) |
| Prenzler25 (2017) | IT Gent (4), VN (1), ELS (5), 1 Myringotomy, 15 BH | Unreported | FES65, HSM | None reported |
| Heywood17 (2016) | Unreported | CN: Freedom (1), ME: Concerto (1) | CNC, CUNY, BKB | None reported |
| Doobe14 (2015) | CI + Lab(5) | Unreported | DHI, SRS | None reported |
| Samy26 (2015) | Unreported | Unreported | CNC, HINT | Dizziness and disabling tinnitus (1) |
| Shi27 (2015) | IT HCTZ, BH, AH (1) | Unreported | Serial audiometry, BKB | None reported |
| Fife15 (2014) | Lab (2), ELS (2) | CN: N24 (1), CI512 (8), CI24RE (3) | HHI, MD-FLS, HINT, AzBio | Device failure (1) |
| MacKeith20 (2014) | CI + Lab(2) | CN: CI500 (2) | PTA, BKB | None reported |
| McRackan3 (2014) | Medical management (13)a, ITCS (2), IT Gent (1), ELS (3), Lab (2) | Unreported | CNC | None reported |
| Mick22 (2014) | Unreported | AB: Clarion 1.2 (2), HR90K (11), HFI(1), CN: N22 (1), N24 (2), ME: Pulsar CI100 (1), Sonata (2) | CID, CUNY, HINT. CNC, THI, SF-36 | New-onset vertigo (1), electrode extrusion (1) |
| Vermeire28 (2014) | Unreported | AB: HR90K (3), CN: CI512 (2), CI24RE (2) | NVA, LIST, NCIQ | New-onset, disabling vertigo (1) |
| Hansen16 (2013) | CI + Lab(10) | CN: CI512 (1), Freedom (2), CI422 (6), AB: HR90K (1) | CNC, AzBio | None reported |
| Holden18 (2012) | IT Dexa, IT Gent, ELS (1) | CN: N24 Contour (1), Freedom (1) | CNC, BKB, sound localization | None reported |
| Lustig19 (2003) | ELS (5), PF (1), Lab (1) | AB: Clarion 1.2 (3), HFI (2), HFCII (2), CN: N22 (1) | Monosyllabic words/phonemes, CID, HINT | Skin flap revision (1), extreme dizziness (1), device failure (1) |
| Morgan23 (1999) | CI + Lab (1) | Digisonic: DX10 (1) | PTA, BKB | None reported |
IT, Intratympanic; Gent, Gentamicin; CI, Cochlear Implant; Lab, Labyrinthectomy;VN, Vestibular Neurectomy; ELS, Endolymphatic Sac Surgery; BH, Betahistine; HCTZ, Hydrochlorothiazide; ITCS, Intratympanic corticosteroid; PF, Perilymphatic fistula; CN, Cochlear (Nucleus); ME, MED-EL; AB, Advanced Bionics; AH, Amiloride Hydrochloride; PTA, Pure tone auditory threshold average; WRS, Word Recognition Score; VHIT, video head impulse test; VMP, vestibular myogenic potentials; HIT, Head impulse test and caloric testing; THI, Tinnitus Handicap Inventory; SRS, Speech Recognition Score; MD-FLS, MD - Functional Level Scale; DHI, Dizziness Handicap Inventory; MDPOSI, MDPatient-Oriented Severity Index; BKB, Bamford-Kowal-Bench test; CUNY, City University of New York test; FES65, Freiburger Einsilber test; HSM, Hochmair-Schulz-Moser test; CNC, Consonant-Nucleus-Consonant word score; HINT, Hearing In Noise Test; HHI, Hearing Handicap Inventory; CID, Central Institute for the Deaf test; SF-36, 36-item Short Form; NVA, Nederlandse Vereniging voor Audiologie monosyllabic word test; LIST, Sentences in quiet and noise test.
Composition of medical management was not provided.