Fig. 2.

Comparison of the latex agglutination test and the lateral flow assay analysing consecutive samples of a case of cryptococcal meningitis. Serum (circles) and CSF (triangles) samples of the only case with discordant CSF measurement results were analysed with the IMMY latex agglutination assay (A) and the CryptoPS lateral flow assay (B), respectively. The X-axis depicts the time course with 0 marking the day of CSF sampling resulting in the first cultural and PCR proof of cryptococcal meningitis (arrows). Dotted lines indicate the cut-off (titre of 1:4 and presence/absence of test line) of the assays. Dashed lines illustrate the course of measurement results. No serum or CSF specimen sampled between the analysed specimens was available