Table 1.
n | % | |
---|---|---|
C. neoformans infection | 25 | |
Sex | ||
Male | 12 | 48 |
Data not available | 9 | 36 |
Mean age (if available to laboratory) | 45 | |
Underlying disease | ||
HIV infection | 19 | 76 |
Immunosuppressive therapy | 3 | 12 |
Congenital immunodeficiency | 1 | 4 |
Risk factors not identified | 1 | 4 |
Information not available | 1 | 4 |
Focus of infection | ||
Meningitis | 14 | 56 |
Blood stream infection | 2 | 8 |
Data not available | 9 | 36 |
Evidence for proven IFI | ||
Culture positivity | 13 | 52 |
CSF antigen positivity | 12 | 48 |
Non-Cryptococcus basidiomycete yeast infection | 2 | 5 |
Male sex | 2 | 100 |
Mean age (in years) | 41 | |
Characteristics of infection | ||
Meningitis by N. albida | 1 | 50 |
Wound infection by F. magnum | 1 | 50 |
Evidence for proven IFI | ||
Culture positivity | 2 | 100 |
No evidence of cryptococcosis | 20 | |
Male sex | 11 | 55 |
Mean age (in years) | 58 | |
Indication for lumbar puncture | ||
Psychiatric assessment | 18 | 90 |
Neurological assessment | 2 | 10 |
Non-Cryptococcus basidiomycete yeast infections included in this study were caused by Naganishia albida (formerly classified as C. albidus) and Filobasidium magnum (formerly classified as C. magnus)