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. 2021 Oct 1;11:19536. doi: 10.1038/s41598-021-97768-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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mRNA expression of IgLON family members in the developing brain. In situ hybridization of coronal sections of brains from E16 embryos with antisense cRNA probes specific for IgLON1 (A), IgLON2 (B), IgLON3 (C), IgLON4 (D), and IgLON5 (E) transcripts. IgLON1–5 are widely expressed in the brain but show differential expression in certain regions, such as the cortex and thalamus. IgLON-1, 2, 3 and 5, are expressed in the developing cortex (Cx), while IgLON1–5 are expressed in the habenula (Hb) and various nuclei of thalamus (Th) (A, B, C, D, E). Scale bar = 1 mm.