Table 2.
Descriptive statistic and comparison of parameters between the groups (independent samples t-test).
| Variable | Control group | Patients with hypertension | Overweight patients with hypertension | Overweight patients with normal blood pressure | |||
|---|---|---|---|---|---|---|---|
| Mean (min, max) | Mean (min, max) | p-value (A and B) | Mean (min, max) | p-value (A and C) | Mean (min, max) | p-value (A and D) | |
| Age [years] | 13.0 (6, 18) | 15.1 (8, 18) | 0.002** | 13.4 (5, 18) | 0.672 | 13.8 (7, 18) | 0.299 |
| Vitamin D [nmol/L] | 78.59 (35.9, 148.5) | 62.7 (7.5, 113.2) | 0.003** | 52.17 (13.5, 90.9) | p < 0.001** | 53.23 (7.5, 83.9) | p < 0.001** |
| BMI percentile | 56 (2, 95) | 64.97 (5.0, 94.0) | 0.114 | 97.56 (91.0, 99.0) | p < 0.001** | 95.69 (86.0, 99.0) | p < 0.001** |
| Systolic pressure [mmHg] | 113 (97, 130 ) | 133 (124, 148) | p < 0.001** | 126 (110, 140) | p < 0.001** | 117 (103, 135) | 0.079 |
| Diastolic pressure [mmHg] | 65 (54, 94) | 75 (61, 93) | p < 0.001** | 69 (55, 77) | p < 0.001** | 67 (47, 79) | 0.732 |
| Homocysteine [μmol/L] | 6.75 (1.8, 15.2) | 7.63 (3.0, 18.2) | 0.139 | 9.38 (5.7, 9.9) | p < 0.001** | 9.46 (7.6, 11.0) | p < 0.001** |
| Total cholesterol [mmol/L] | 4.53 (2.9, 6.95) | 4.21 (2.78, 6.10) | 0.051 | 4.66 (2.29, 6.94) | 0.472 | 4.57 (3.35, 6.33) | 0.830 |
| LDL cholesterol [mmol/L] | 2.73 (1.38, 4.9) | 2.48 (1.5, 4.0) | 0.091 | 3.01 (0.9, 5.10) | 0.074 | 2.92 (1.90, 4.50) | 0.211 |
| HDL cholesterol [mmol/L] | 1.57 (0.76, 2.25) | 1.46 (0.89, 2.53) | 0.130 | 1.32 (0.8, 2.66) | 0.002** | 1.29 (0.81, 2.23) | 0.001** |
| TG [mmol/L] | 0.87 (0.34, 1.67) | 1.03 (0.45, 2.61) | 0.089 | 1.29 (0.30, 4.18) | 0.001** | 1.11 (0.57, 3.31) | 0.022* |
| Uric acid [μmol/L] | 262.0 (121.0, 424.0) | 310.0 (101.0, 436.0) | 0.006** | 336.75 (187.0, 534.0) | p < 0.001** | 322.0 (166.0, 477.0) | 0.001** |
| Glucose [mmol/L] | 4.76 (1.42, 6.4) | 4.71 (4.1, 5.6) | 0.628 | 4.71 (3.6, 5.9) | 0.666 | 4.77 (3.6, 5.4) | 0.957 |
| ApoA [g/L] | 1.64 (1.04, 6.87) | 1.42 (0.99, 1.94) | 0.101 | 1.37 (1.07, 1.77) | 0.029* | 1.36 (1.06, 1.62) | 0.036* |
| ApoB [g/L] | 0.69 (0.4, 1.10) | 0.70 (0.47, 1.1) | 0.678 | 0.82 (0.29, 1.33) | 0.003** | 0.83 (0.40, 1.58) | 0.009** |
| Alkaline phosphatase [µkat/L] | 3.33 (1.04, 6.87) | 3.34 (0.91, 9.64) | 0.995 | 3.17 (0.98, 6.24) | 0.649 | 3.26 (1.36, 6.83) | 0.858 |
| Calcium [mmol/L] | 2.39 (2.23, 2.75) | 2.42 (2.22, 2.64) | 0.110 | 2.39 (2.20, 2.52) | 0.741 | 2.34 (1.57, 2.54) | 0.173 |
| Phosphate [mmol/L] | 1.38 (0.85, 1.85) | 1.28 (0.74, 1.80) | 0.043* | 1.34 (0.75, 1.9) | 0.472 | 1.33 (0.77, 2.44) | 0.471 |
| Magnesium [mmol/L] | 0.9 (0.73, 1.28) | 0.89 (0.67, 1.05) | 0.673 | 0.92 (0.71, 1.07) | 0.228 | 0.89 (0.32, 1.32) | 0.648 |
Control group (A), children with hypertension (B), overweight children with hypertension (C) and overweight children with normal blood pressure (D). Value p represents the comparison between the control group and all the other groups studied.
Min minimal, max maximal, BMI Percentile body mass index percentile, LDL cholesterol low-density lipoprotein cholesterol, HDL cholesterol high-density lipoprotein cholesterol, TG triglycerides, ApoA apolipoprotein A1, ApoB apolipoprotein B.
*p < 0.05, **p < 0.01.