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. 2021 Oct 1;11:19576. doi: 10.1038/s41598-021-98031-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mutational profiling and functional impact in oral cancer. (a) We have performed pathway enrichment analysis for those genes which appear to have more than 5% mutation for the selected dataset from TCGA database; (b) Genes with mutations ≥ 10%; (c) Comparison of the altered functions with respect to mutations and differential expression; (d) p-value for Kaplan-Meyer plots after survival analysis of the hypoxic genes in case of head and neck cancer.