Figure 6.

Ablation and medication therapy; (A) Thermal ablation forms three regions: coagulative necrosis (α), sublethal necrosis (β), and the region in which cells are not affected (γ). (B) Perfusion damage due to thermal ablation; the perfusion is zero in the α region, the perfusion yield is less than 25% in the β region, and the perfusion yield is half in the γ region. This contour indicates perfusion and vascular density. (C) Spatial distribution of the drug in the combination of thermochemotherapy and thermal ablation. (D) Spatial distribution of the therapeutic agents in the combination of ThermoDox therapy and thermal ablation.