Table 4:
MaAsLin2 Analysis of Hospitalizations in Patients with Cirrhosis
| Genus-level | Family-level | ||||||
|---|---|---|---|---|---|---|---|
| Feature | Coefficient | P-value | Q-value | Feature | Coefficient | P-value | Q-value |
| Brachyspira | 7.710336 | 5.44E-09 | 1.87E-06 | Brachyspiraceae | 7.729541 | 5.01E-09 | 6.66E-07 |
| MELD score | 0.389873 | 3.32E-07 | 5.70E-05 | Initial MELD | 0.389873 | 3.32E-07 | 2.21E-05 |
| Kosakonia | 6.368388 | 1.20E-06 | 0.000137 | Enterococcaceae | 3.228292 | 1.02E-06 | 4.50E-05 |
| Anaerofilum | 2.340699 | 1.61E-06 | 0.000138 | Prior HE | 1.079602 | 1.97E-05 | 0.000655 |
| Prior HE | 1.079602 | 1.97E-05 | 0.001352 | Rice | −0.76889 | 0.000281 | 0.007471 |
| Ruminococcus | −2.46194 | 5.68E-05 | 0.002783 | USA1-BRA2 | −0.22077 | 0.00076 | 0.016853 |
| Salmonella | 3.196077 | 5.08E-05 | 0.002783 | Coffee | −0.42314 | 0.001514 | 0.028762 |
| Enterococcus | 3.742249 | 7.30E-05 | 0.003132 | ||||
| Rice | −0.76889 | 0.000281 | 0.010705 | ||||
| Atopobium | 2.989837 | 0.000526 | 0.016407 | ||||
| Dorea | −1.07421 | 0.000526 | 0.016407 | ||||
| USA1-BRA2 | −0.22077 | 0.00076 | 0.021732 | ||||
| Coffee | −0.42314 | 0.001514 | 0.039941 | ||||
Positive coefficient indicates associated with hospitalization while negative coefficient indicates protection from hospitalization. Brazil was coded as 2 and USA as 1 so negative indicates lower hospitalizations in Brazil-origin patients with cirrhosis.