Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Human Cohort 2 Participant Characteristics (n = 7)
| Age, y (at start of study) | 36 ± 6 |
| Female | 3 (43) |
| BMI, kg/m2 | 23 ± 3 |
| Plasma profile at baseline (before PCSK9i therapy) | |
| PCSK9, ng/mL | 214 ± 121 |
| Total cholesterol, mg/dL | 184 ± 45 |
| LDL-C, mg/dL | 104 ± 31 |
| HDL-C, mg/dL | 65 ± 18 |
| Triglycerides, mg/dL | 71 ± 19 |
| PCSK9i single injection | |
| Alirocumab (75 mg) | 3 |
| Evolocumab (140 mg) | 4 |
Values are mean ± SD, n (%), or n.
Abbreviations as in Table 1.
