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. 2021 Aug 2;3(3):96–102. doi: 10.2991/chi.k.210718.001

Table 3.

Levels of high sensitivity troponin T (hsTropT) and N-terminal pro-B natriuretic peptide (NTproBNP) among 40 patients who underwent chimeric antigen receptor (CAR) T cell therapy. a b c represent the lower quartile a, the median b, and the upper quartile c. (A and B) Levels of hsTropT and NTproBNP at baseline (BL), day 1, days 7 and 21. (C and D) Levels of hsTropT and NTproBNP stratified by whether patients experienced grade 2 cytokine release syndrome or not (E) Levels of hsTropT stratified by whether it was abnormal (>14 ng/L) at baseline or not. (F) Levels of NTproBNP stratified by whether it was abnormal (>125 pg/mL) at baseline or not

hsTropT levels: Overall NTproBNP levels: Overall


Day Full group (n = 40) Day Full group (n = 40)

BL 9.212.120.1 BL 116.0179.1324.8
1 9.613.124.2 1 97.8357.2813.4
7 9.611.918.0 7 238.6420.01241.5
21 10.815.320.2 21 79.7176.8278.4

hsTropT levels: by grade 2 CRS vs. not NTproBNP levels: by grade 2 CRS vs. not


Day No CRS (n = 22) Yes CRS (n = 18) Day No CRS (n = 22) Yes CRS (n = 18)

BL 8.913.121.3 9.211.318.0 BL 136.4213.9427.6 91.5178.9291.3
1 9.912.625.0 9.513.519.6 1 169.6368.2710.8 78.0344.41293.5
7 10.513.017.6 9.311.419.1 7 166.0373.6711.5 393.7949.31381.8
21 10.215.320.8 11.315.319.2 21 77.5146.4212.7 150.9206.6334.5

hsTropT levels: by abnormal vs. normal baseline hsTropT NTproBNP levels: by abnormal vs. normal baseline NTproBNP


Day Normal baseline hsTropT (n = 20) Abnormal baseline hsTropT (n = 17) Day Normal baseline hsTropT (n = 20) Abnormal baseline hsTropT (n = 17)

BL 7.39.310.2 16.721.025.2 BL 48.184.5102.1 179.0276.4485.1
1 8.710.011.5 16.425.032.7 1 55.274.8113.8 322.9679.01340.0
7 8.810.411.6 13.817.824.0 7 109.6260.7410.8 383.9949.22164.0
21 9.110.813.6 16.920.823.6 21 52.1120.3158.2 138.1210.9424.6