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. 2021 Sep 17;10(9):e27799. doi: 10.2196/27799

Table 1.

Research questions.

Research questions Operational definitions
What is the representation of vulnerable individuals in the intended target population for any study on artificial intelligence within primary care? Vulnerable populations are defined as those with known disparities as described by the following categories:
  • Place of residence (eg, rural)

  • Race, ethnicity (eg, Black)

  • Occupation (eg, coal miners)

  • Gender, sex (eg, transgender)

  • Religion (eg, Amish)

  • Education (eg, high-school only)

  • Socioeconomic status (eg, low income)

  • Social capital (eg, isolation)

How well do current studies on artificial intelligence in primary care report different types of bias that may be perpetuated as health disparities by their systems? Data extraction elements (Table 2)
What interventions do current studies on artificial intelligence in primary care use to address harmful effects of pre-existing biases in their systems? Example interventions are listed below:
  • Preprocessing

  • Modified data sources

  • Preprocessing data for fairness

  • Model development

  • Demographic parity

  • Equalized odds/opportunity

  • Disparity regularization

  • Counterfactual fairness

  • Postprocessing

  • Subgroup analysis

  • Meta-regression

  • Quality assurance