Fig. 5.

MTHFD2 regulates ovarian cancer cell progression via STAT3 pathway. (A) Protein expression levels of p‐STAT3, STAT3, N‐cadherin, and Vimentin as tested by western blot in the indicated cells with knockdown of MTHFD2 using the indicated siRNAs. (B) Protein expression levels of p‐STAT3 and STAT3 as tested by western blot in SKOV3 cells and OVCAR8 cells with overexpression of MTHFD2 using the plasmid The experiments were repeated three times independently. (C) Schematic diagram of the MTHFD2/STAT3 regulatory pathways in cells.