Table 1.

Summary of mechanism of action of each micronutrient.

Micronutrient	Proposed Mechanism of Action
Melatonin	Down regulates pro-inflammatory cytokines such as IL-2,6,12,TNF-$\alpha$, IFN-$\gamma$ and NF-k$\beta$
Zinc	1) Reduces the production of inflammatory cytokines 2) Stimulate CD8+ T cells 3) Inhibits RNA dependent RNA polymerase
Selenium	1) Decreases IL-1$\beta$ and IL-6 production 2) Decreases platelet formation and potential thrombus formation
Vitamin C	Protects cells against oxidative damage by scavenging reactive oxygen species
Vitamin D	1) Response from innate and adaptive immune system 2) Formation of gap junctions