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. 2021 Oct 2;144:104993. doi: 10.1016/j.jcv.2021.104993

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© 2021 The Authors. Published by Elsevier B.V.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig 3 — Graphical representation of mean sequence depth obtained using EasySeq™ RC-PCR SARS-CoV-2 WGS kit over multiple illumina sequence runs and versions. The line graph represents the mean sequence depth in log₁₀ scale of the SARS-CoV-2 genome. The top two graphs are based on data produced using v1 kit of EasySeq™, middle two graphs are based on data using v2 and the last two of v3. Below each plot a representation of the SARS-CoV-2 ORFs are given. 25 and 51 indicate the amplicons dropouts in v1. ORF1ab:S675_F3677- and S:HV69–70- low coverage is due to a known deletions in B.1.1.7 (alpha).