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. 2021 Oct 1;3:44. doi: 10.1186/s42238-021-00103-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Larval locomotion following exposure to high THC, high CBD, low-temp THC:CBD, and high-temp THC:CBD extracts. A–D Larval behavioral profiles following exposure to extracts at varying concentrations during the alternating 5-min light/dark cycles. The average distance traveled is presented in millimeters per 1 min bin ± standard error (SEM) and time in minutes. E Difference in the average distance traveled between the first 5-min dark cycle and the preceding 5-min light. Average distance ± SEM is presented in millimeters per 5 min bin and time in minutes. Each bar represents an n = 36 (extract) to 96 (control) larvae. *Significant difference from experimental control as measured by ANOVA followed by a Bonferroni post hoc test (p < 0.05)