Table 2.
Factors associated with viral suppression (n = 831)
| Variables | n (%) | Viral load suppressed n = 751 | Viral load unsuppressed n = 80 | P value |
|---|---|---|---|---|
| Baseline CD4 counts (cells/µl) * | ||||
| < 500 | 404 (48.6) | 346 (46.1) | 58 (72.5) | < 0.001 |
| ≥ 500 | 427 (51.4) | 405 (53.9) | 22 (27.5) | |
| Years on HAART | ||||
| < 5 years | 354 (42.6) | 325 (43.3) | 29 (36.3) | 0.237 |
| ≥ 5 years | 477 (57.4) | 426 (56.7) | 51 (63.7) | |
| HAART Regimen | ||||
| First Line | 793 (95.4) | 728 (96.9) | 65 (81.3) | < 0.001 |
| Second Line | 38 (4.6) | 23 (3.1) | 15 (18.7) | |
| TB confirmed** | ||||
| Yes | 21 (2.5) | 19 (2.8) | 2 (2.8) | 1.000f |
| No | 731 (88.0) | 662 (97.2) | 69 (97.2) | |
| Missing | 79 (9.5) | |||
| Disease stage | ||||
| WHO stages 1 and 2 | 809 (97.4) | 732 (97.5) | 77 (96.3) | 0.461f |
| WHO stages 3 and 4 | 22 (2.6) | 19 (2.5) | 3 (3.7) | |
| Pregnancy Status (n = 578) | ||||
| Not Pregnant | 558 (96.5) | 501 (96.7) | 57 (95.0) | 0.452f |
| Pregnant | 20 (3.5) | 17 (3.3) | 3 (5.0) | |
|
Viral Load (cp/ml) Median (IQR) |
20 (20–74) Range (20 to 2,469,613) |
20 (20–40) Range (20 to 925) |
19,989 (3311 to 110,340) Range (1170 to 2,468,443.0) |
< 0.001 |
|
2019 Viral Load (cp/ml) Median (IQR) |
20 (20–70.5) Range (20 to 2,469,613) N = 744 |
20 (20–40) Range (20 to 845) N = 674 |
17,086.5 (3228.8–131,695 Range (1170 to 2,469,613) N = 70 |
< 0.001 |
|
2018 Viral Load (cp/ml) Median (IQR) |
20 (20–119) Range (20 to 112,454) N = 87 |
20 (20–39.5) Range (20 to 925) N = 77 |
31,997.0 (4205.5–68,372.0) Range (1373 to 112,454) N = 10 |
< 0.001 |
*Baseline value of CD4 count at enrollment (Prior to the commencement of anti-retroviral therapy-ART); **TB confirmed cases among those with viral load suppression; IQR-Interquartile range; f-Fischer exact test