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. 2021 Sep 30;9(1):e002348. doi: 10.1136/bmjdrc-2021-002348

Table 1.

Comparison of patients’ demographic and medical characteristics by medication complexity

Low complexity Moderate complexity High complexity P value
Age (years) 62.6±10.4 58.9±10.2 56.7±10.3 0.13
Gender 0.51
 Male 15 (57.7) 12 (54.5) 11 (42.3)
 Female 11 (42.3) 10 (45.5) 15 (57.7)
Race/ethnicity (self-reported)* 0.38
 White or Caucasian 4 (15.4) 4 (20) 2 (7.7)
 Black/African American 2 (15.4) 5 (25) 2 (7.7)
 Hispanic 18 (69.2) 11 (55) 21 (80.8)
 Native Hawaiian/Pacific Islander 0 0 1 (3.8)
BMI (kg/m2) 31.3±5.2 32.1±6.5 34.6±5.2 0.09
Systolic BP (mm Hg) 132±15.3 127.6±13.5 131.8±17.3 0.56
Diastolic BP (mm Hg) 70.1±10.9 71.3±10.9 70.5±10.8 0.93
Duration of diabetes (years) 11.4±9.8 13.6±9.1 13.8±7.6 0.55
HbA1c (%)† 7.4±1.2 8.7±1.5 8.6±2 0.006
Creatinine (mg/dL)‡ 0.88±0.24 0.9±0.27 1.0±0.32 0.5
eGFR (mL/min)§ 79.4±17.9 84.7±24.5 83.1±19.9 0.72
LDL (mg/dL)¶ 92.8±38.1 97.8±25.2 85±33.9 0.59
Diabetes distress score (range 2–12) 4.7±2.8 4.6±2.8 6.8±2.9 0.009
Diabetes distress 0.02
 DDS-2<6 17 (65.4) 14 (63.6) 8 (30.8)
 DDS-2≥6 9 (34.6) 8 (36.4) 18 (69.2)
Hypertension 0.36
 No 4 (15.4) 7 (31.8) 5 (19.2)
 Yes 22 (84.6) 15 (68.2) 21 (80.8)
Hyperlipidemia* 0.97
 No 7 (29.2) 6 (27.3) 8 (30.8)
 Yes 17 (70.8) 16 (72.7) 18 (69.2)
Hypoglycemia 0.1
 No 21 (80.8) 13 (59.1) 14 (53.8)
 Yes 5 (19.2) 9 (40.9) 12 (46.2)
Microvascular complications** 0.003
 No 18 (72) 11 (55) 6 (24)
 Yes 7 (28) 9 (45) 19 (76)
Macrovascular complications†† 0.43
 No 20 (87) 20 (95.2) 19 (82.6)
 Yes 3 (13) 1 (4.8) 4 (17.4)

*n=72.

†n=73.

‡n=61.

§n=54.

¶n=47.

**n=70.

††n=67.

BMI, body mass index; BP, blood pressure; DDS-2, Diabetes Distress Scale-2; eGFR, estimated glomerular filtration rate; LDL, low density lipoprotein.