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. 2021 Sep 30;11(9):e044605. doi: 10.1136/bmjopen-2020-044605

Table 3.

Analytical data of prognostic factors for all-cause mortality or admission for heart failure in patients with heart failure and preserved ejection fraction

ROC curve analysis Cox hazard analysis
Univariable Multivariable
Cut-off point AUC Ratio 95% CI P value Ratio 95% CI P value
Age 85 0.628 2.855 1.634 to 4.99 <0.001 1.736 0.934 to 3.225 0.081
Sex 0.965 0.547 to 1.701 0.903 1.223 0.638 to 2.345 0.544
NT-proBNP 783 0.695 3.432 1.652 to 7.133 <0.001 3.152 1.422 to 6.987 0.004
LAVI 38 0.607 2.225 1.134 to 4.366 0.02 1.298 0.599 to 2.813 0.508
Ed/Ea 0.121 0.637 2.424 1.337 to 4.394 0.003 2.034 1.059 to 3.907 0.032

AUC, area under the curve; Ea, arterial elastance; Ed, diastolic elastance; LAVI, left atrial volume index; NT-proBNP, N-terminal pro-brain natriuretic peptide; ROC, receiver operating characteristic.