Table 1.
Baseline characteristics
Characteristic | N | % |
Median age, years (range) | 64 (34–80) | |
Sex | ||
Male | 39 | 79.6 |
Female | 10 | 20.4 |
Race | ||
White | 44 | 89.8 |
Black or African American | 2 | 4.1 |
Asian | 1 | 2.0 |
Other | 1 | 2.0 |
More than one race | 1 | 2.0 |
ECOG performance status | ||
0 | 13 | 26.5 |
1 | 36 | 73.5 |
Histology at baseline | ||
Squamous cell carcinoma | 10 | 20.4 |
Adenocarcinoma (including one adenosquamous) | 39 | 79.6 |
Metastatic disease | ||
Yes | 45 | 91.8 |
No | 4 | 8.2 |
Prior radiation therapy | ||
Received | 33 | 67.3 |
Not received (or unknown) | 16 | 32.7 |
Prior lines of therapy | ||
0 | 0 | 0.0 |
1 | 10 | 20.4 |
2 | 13 | 26.5 |
3 | 9 | 18.4 |
4 | 8 | 16.3 |
≥5 | 7 | 14.3 |
Missing | 2 | 4.1 |
HER2 (EAC only) | ||
Negative | 29 | 74.4 |
Positive | 9 | 23.1 |
Unknown | 1 | 2. |
MMR status | ||
MMR proficient | 9 | 18.4 |
MLH1 proficient, not tested otherwise | 1 | 2.0 |
MMR deficient | 1 | 2.0 |
Unknown | 38 | 77.6 |
ECOG, Eastern Cooperative Oncology Group; MMR, mismatch repair.