Table 2.
Baseline remission | Odds ratio | P-value | 95% CI |
---|---|---|---|
Age | 0.98 | <0.0001 | 0.97, 0.99 |
Female gender | 0.67 | <0.0001 | 0.55, 0.82 |
BAME | 0.95 | 0.7 | 0.70, 1.29 |
Smoking (ref: current smoker) | |||
Ex-smoker | 0.88 | 0.4 | 0.66, 1.17 |
Never smoked | 0.89 | 0.4 | 0.69, 1.16 |
Paid work | 1.42 | 0.002 | 1.13, 1.78 |
IMD | 1.08 | <0.0001 | 1.04, 1.13 |
Comorbidity | 0.83 | 0.002 | 0.74, 0.94 |
Seropositive | 0.98 | 0.9 | 0.81, 1.20 |
Symptom duration (ref: <1 month) | |||
1, 6 months | 0.60 | 0.002 | 0.43, 0.83 |
>6 months | 0.72 | 0.06 | 0.51, 1.01 |
Referred via EIA pathway | 0.90 | 0.3 | 0.73, 1.11 |
Prompt referral | 0.90 | 0.3 | 0.73, 1.11 |
Prompt specialist review | 0.75 | 0.008 | 0.61, 0.93 |
Baseline remission implies a DAS28 at diagnosis <2.6. Lower age, male gender, paid work, high SEP, fewer comorbidities, and prompt rheumatology review all associated with baseline remission. Symptom duration also appeared to associate with remission, but the relationship was non-linear. Prompt referral was defined as a referral that was sent within three days of primary care review. Prompt review was defined as a rheumatology review within 21 days of primary care referral receipt. BAME: black, Asian, and minority ethnic; IMD: index of multiple deprivation.