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Network meta-analysis of the rate ratio of serious adverse events
Network meta-analysis allows indirect comparisons of serious adverse events between treatment strategies. Treatment effects are described comparing the first ( left-hand) strategy with the second ( right-hand) strategy. The first seven strategies were compared with the reference arm, which was MTX + placebo, based on studies with direct comparisons. bDMARD: biologic DMARD; tsDMARD: targeted synthetic DMARD.
