Table 2.

Treatment-Related Adverse Events in ≥ 10% of Patients

Adverse Event	Grade 1	Grade 2	Grade 3	Total
Anemia	1 (3)	5 (19)	7 (27)	13 (50)
Neutrophil count decreased	-	4 (15)	6 (23)	10 (39)
Fatigue	6 (23)	3 (11)	-	9 (35)
WBC decreased	4 (15)	4 (15)	1 (4)	9 (35)
Platelet count decreased	5 (19)	2 (8)	1 (4)	8 (31)
Aspartate aminotransferase increased	2 (8)	1 (4)	1 (4)	4 (15)
Diarrhea	2 (8)	2 (8)	-	4 (15)
Alanine aminotransferase increased	1 (3)	1 (3)	1 (3)	3 (11)
Bloating	-	3 (11)	-	3 (11)
Weight gain	1 (3)	2 (8)		3 (11)
Dizziness	2 (8)	1 (3)		3 (11)
Generalized muscle weakness	2 (8)	1 (3)		3 (11)
Blood and Lymphatic system disorders	3 (11)			3 (11)
Dyspnea	2 (8)	1 (3)		3 (11)

Abbreviations: WBC: white blood cell