Table 2.
Multivariable risk-adjusted predictive model for short- and long-term mortality
| Variables | ICU Mortality OR (95% CI) | Hospital Mortality OR (95% CI) | 28-day Mortality OR (95% CI) |
|---|---|---|---|
| Age, (per 1-year increase) | 1.049 (1.032–1.066) | 1.050 (1.033–1.068) | 1.058 (1.035–1.081) |
| Male | |||
| Diabetes mellitus | 1.546 (1.084–2.203) | 1.626 (1.093–2.420) | |
| Chronic steroids | 3.697 (1.633–8.371) | ||
| SAPS3, (per 1-point increase) | 1.025 (1.008–1.041) | 1.027 (1.011–1.044) | |
| N:L ratio (per 1-unit increase) | 1.009 (1.002–1.016) | 1.008 (1.000–1.016) | |
| Failed attempt of NPPV prior to orotracheal intubation | 2.131 (1.279–3.550) | 1.878 (1.123–3.39) | |
| Selective Digestive Decontamination strategy | 0.587 (0.358–0.963) | 0.591 (0.358–0.972) | |
| Need of vasopressor support | 1.878 (1.119–3.152) | 2.042 (1.205–3.460) | 2.158 (1.197–3.891) |
| Methylprednisolone < 1 mg/kg | 0.500 (0.302–0.828) | ||
| Methylprednisolone > 1 mg/kg | 0.479 (0.283–0.811) | ||
| AUC (95% CI) | 0.712 (0.677; 0.746) |
0.728 (0.694; 0.761) |
0.746 (0.705; 0.787) |
| Calibration, CITL (95% CI) | 0.001 (-0.306; 0.308) |
0.0007 (-0.312;0.313) |
< 0.001 (-0.398; 0.398) |
| Slope (95% CI) | 1.025 (0.822; 1.228) | 1.018 (0.827; 1.209) | 1.000 (0.788; 1.214) |
SAPS, Simplified Acute Physiology Score; NPPV: noninvasive positive pressure ventilation; N: L, neutrophil to lymphocyte ratio; AUC; area under the curve. OR, Odds Ratio; CI, confidence interval