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. 2021 Oct 2;37:28. doi: 10.1186/s42826-021-00105-0

Fig. 2.

Fig. 2

Increased inflammatory infiltrates accompanied by fibrotic changes in BLM-induced pulmonary fibrosis in mice. Mice were intratracheally injected BLM (1, 3 mg/kg) for 1 and 2 weeks. a Represented images showed collagen accumulation of lung by Masson’s trichrome staining. b The mRNA relative level of fibrosis marker was confirmed by real-time quantitative PCR. Western blot conclusion analysis determined accumulation of α-SMA in the c 1 ml/kg and (D) 3 ml/kg BLM treated lung. The intensity was quantified by Image J software. *p < 0.05 and **p < 0.01 compared with CTL