Table 2.

Association of different classifications for CAD with all-causes mortality in the study

	Univariable cox		Multivariable cox
	HR (95%)	P value	HR (95%)	P value
Traditional CAD classification 1
No CAD	1 (ref)
Mild CAD	2.508 (1.999–3.147)	< 0.001	1.376 (1.087–1.742)	0.008
Moderate CAD	3.829 (2.901–5.055)	< 0.001	1.572 (1.172–2.109)	0.003
Severe CAD	7.024 (5.449–9.053)	< 0.001	2.563 (1.950–3.370)	< 0.001
Traditional CAD classification 2
Normal	1 (ref)
Mildly abnormal	2.789 (2.250–3.458)	< 0.001	1.420 (1.132–1.782)	0.002
Moderately abnormal	7.045 (4.713–10.531)	< 0.001	2.825 (1.871–4.266)	< 0.001
Severely abnormal	7.015 (5.342–9.213)	< 0.001	2.465 (1.841–3.301)	< 0.001
Traditional CAD classification 3
No CAD	1 (ref)
Nonobstructive CAD	2.508 (1.999–3.147)	< 0.001	1.382 (1.092–1.750)	0.007
1 vessel obstructive CAD	3.243 (2.424–4.338)	< 0.001	1.406 (1.036–1.908)	0.029
2 vessel obstructive CAD	7.403 (5.426–10.100)	< 0.001	2.689 (1.937–3.734)	< 0.001
3 vessel/LM obstructive CAD	8.211 (6.145–10.971)	< 0.001	2.756 (2.024–3.752)	< 0.001
Duke CAD index
0	1 (ref)
1	1.876 (1.425–2.470)	< 0.001	1.210 (0.915–1.601)	0.181
2	3.349 (2.595–4.320)	< 0.001	1.568 (1.200–2.049)	0.001
3	3.019 (2.175–4.189)	< 0.001	1.334 (0.949–1.875)	0.097
4	6.336 (4.512–8.898)	< 0.001	2.408 (1.689–3.433)	< 0.001
5	6.120 (4.401–8.511)	< 0.001	2.355 (1.667–3.326)	< 0.001
6	6.267 (3.936–9.979)	< 0.001	2.313 (1.438–3.719)	< 0.001
7	9.505 (6.654–13.578)	< 0.001	3.095 (2.127–4.505)	< 0.001
CAD-RADS
0	1 (ref)
1	1.250 (0.610–2.561)	0.541	0.861 (0.420–1.764)	0.682
2	2.610 (2.077–3.280)	< 0.001	1.412 (1.113–1.792)	0.004
3	3.828 (2.900–5.053)	< 0.001	1.577 (1.176–2.116)	0.002
4A	6.412 (4.770–8.620)	< 0.001	2.449 (1.792–3.347)	< 0.001
4B&5	8.049 (5.813–11.145)	< 0.001	2.761 (1.961–3.887)	< 0.001

Multivariable cox models were adjusted for patient age and sex

CAD coronary artery disease, CAD-RADS Coronary Artery Disease-Reporting and Data System