Table 2. Dosimetry details of 37 radioembolizations in 28 patients with intrahepatic cholangiocarcinoma.
Segmental radioembolization >190 Gy
18 patients, 24 treatment sessions | ||||||
---|---|---|---|---|---|---|
Patient | Radioembolization
sessions |
Number of angiosomes | Volume (mL) | Activity (GBq) | Dose (Gy) | |
1 | 1 | 3 | 192 | 1.9 | 398.1 | |
2 | 1 | 1 | 400 | 2.1 | 256.6 | |
3 | 1 | 2 | 572 | 4.4 | 278.1 | |
5 | 1 | 2 | 1015 | 3.6 | 256.9 | |
7 | 1 | 1 | 31 | 0.2 | 347.4 | |
8 | 2 | First | 4 | 1010 | 4.6 | 220.5 |
Second | 4 | 250 | 1.3 | 248 | ||
9 | 1 | 1 | 89.2 | 1.5 | 807.8 | |
11 | 1 | 2 | 315 | 3.1 | 476.8 | |
12 | 1 | 2 | 591 | 2.6 | 213.5 | |
13 | 2 | First | 1 | 450 | 1.69 | 182.7* |
Second | 4 | 1250 | 2.57 | 464.8 | ||
16 | 3 | First | 3 | 360 | 1.3 | 170.9* |
Second | 2 | 398 | 1.8 | 219.3 | ||
Third | 3 | 224 | 1.3 | 289.5 | ||
18 | 1 | 4 | 285 | 1.0 | 221.0 | |
19 | 2 | First | 1 | 220 | 1.1 | 246.1 |
Second | 1 | 85 | 0.8 | 464.1 | ||
23 | 1 | 3 | 299 | 1.5 | 250.2 | |
25 | 1 | 2 | 300 | 1.3 | 210.5 | |
26 | 1 | 1 | 123 | 0.6 | 251.9 | |
27 | 2 | First | 3 | 180 | 1.4 | 362.7 |
Second | 1 | 221 | 1.3 | 247.6 | ||
28 | 1 | 2 | 398 | 2.4 | 287.6 | |
Lobar >190 Gy (n = 5)
5 patients, 5 treatment sessions | ||||||
Patient | Radioembolization sessions | Number of angiosomes treated | Volume (mL) | Activity (GBq) | Dose (Gy) | |
4** | 1 | 1 | 340 | 2.6 | 372.6 | |
6** | 1 | 1 | 582 | 2.4 | 197.2 | |
10** | 1 | 1 | 1070 | 4.97 | 225.2 | |
22 | 1 | 1 | 1210 | 9.1 | 363.6 | |
24 | 1 | 1 | 504 | 2.4 | 220.3 | |
Lobar <190 Gy + segmental >190 Gy
5 patients, 5 treatment sessions | ||||||
Patient | Radioembolization sessions | Number of angiosomes treated | Volume (mL) | Activity (GBq) | Dose (Gy) | |
4** | 1 | 2 | 675 | 0.9 | 198.6 | |
6** | 1 | 2 | 700 | 3.3 | 232.1 | |
14 | 1 | 4 | 1636 | 6.6 | 195.7 | |
15 | 1 | 2 | 978 | 4.9 | 244.2 | |
17 | 1 | 2 | 650 | 2.6 | 218.0 | |
Lobar >190 Gy + segmental >190 Gy
3 patients, 3 treatment sessions | ||||||
Patient | Radioembolization sessions | Number of angiosomes treated | Volume (mL) | Activity (GBq) | Dose (Gy) | |
10** | 1 | 2 | 952 | 4.4 | 225.5 | |
20 | 1 | 2 | 250 | 1.3 | 254.5 | |
21 | 1 | 3 | 467 | 2.8 | 290.1 |
*Those with <190 Gy MIRD in a particular treatment had more than one treatment and a cumulative dose >190 Gy to the targeted vascular territory (as stated in the Methods section). **Patient 4 received 1 lobar > 190 Gy and 1 Lobar <190 Gy + segmental >190 Gy, patient 6 received 1 lobar > 190 Gy and 1 Lobar <190 Gy + segmental >190 Gy, and patient 10 received 1 lobar > 190 Gy and 1 Lobar >190 Gy + segmental >190 Gy.