Figure 4. Generation of both effector and memory T cells in MM patients and HDs following peptide activation.

Flow cytometry dot plots depicting (A) CD4⁺ and (B) CD8⁺ T_EM (CD45RO⁺CD62L^-) and T_CM (CD45RO⁺CD62L⁺) for HD and MM on D19 following stimulation of multipeptide cocktails. Representative data shown for 2 individuals. (C) Chart showing composite results of T_EM and T_CM for MUC1-activated HD (top) and MM patients (bottom). Statistical analysis indicated no significant differences (Student’s t-test).