Table 1. Mutational background of selected colon cancer cell lines.

CRC Cell Line Name	Species	MSI/MSS status	TP53	HRAS	NRAS	KRAS	BRAF	PIK3CA	PTEN expression	APC	TRK	CTNNB1	ACVR2A	BRCA2	TGFBR2
HCT-116	human	MSI	WT	WT	WT	MT	WT	MT	positive	WT	WT	MT	MT	MT	WT
HT-29	human	MSS	MT	WT	WT	WT	MT	MT	positive	MT	WT	WT	WT	WT	MT
KM12C	human	MSI	MT	WT	WT	WT	WT	WT	null	MT	MT	UN	MT	MT	MT

Abbreviation: WT: wild type; MT: mutant; UN: unknown. HCT-116, HT-29, and KM12C colon cancer cell line mutational backgrounds.