Figure 5. Drug-specific gene signatures divided into p53-independent and p53-dependent subsets after 5-FU, CPT-11, oxaliplatin, and cisplatin treatment of human colorectal cancer cells.

Drug-specific signatures from Figure 4 were divided into p53-independent and p53-dependent subsets using the filtering method in Figure 2C. Drug-specific effects of (A) 5-FU, (B) CPT-11, and (C) oxaliplatin are shown.