Figure 6. Cisplatin-specific and 5-FU/CPT-11/oxaliplatin-specific gene signatures.

(A) Transcripts that are differentially regulated by cisplatin and oxaliplatin. (B) Cisplatin-specific gene signature divided into p53-independent and p53-dependent subsets. (C) 5-FU/CPT-11/oxaliplatin-specific signature contains transcripts that are upregulated by 5-FU, CPT-11, and oxaliplatin but are unaffected by cisplatin.