Table 5:
Association between APOL1 genotype and key kidney parameters.
| Risk allele category a | Odds Ratio (95% CI) b | ||
|---|---|---|---|
| uACR | eGFR | Serum creatinine | |
| 1 risk allele | 0.78 (0.67, 0.92) | 1.02 (0.87, 1.20) | 1.04 (0.88, 1.22) |
| 2 risk alleles | 1.96 (1.41, 2.72) | 1.25 (0.90, 1.72) | 1.18 (0.85, 1.65) |
Reference Levels: 0 Risk Alleles (No alleles).
From cumulative probability models including the outcome as a continuous variable. All models are adjusted for age, sex, ethnicity, current tenofovir use, CD4 cell count, viral load, diabetes mellitus status, hypertension status, congestive heart failure status, other comorbid condition status, current ACEi/ARB use, current smoking, body mass index, and JNC blood pressure category