Table 1.
Characteristics of older patients with digestive system cancer, by period.
| Pre-lockdown period January 1st –March 16th (N = 2763) |
Overall p | Lockdown period March 17th –May 10th (N = 1668) |
Overall p | Post-lockdown period May 11th –August 30th (N = 3451) |
Overall p | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018 N = 960 |
2019 N = 889 |
2020 N = 914 |
2018 N = 650 |
2019 N = 645 |
2020 N = 373 |
2018 N = 1247 |
2019 N = 1192 |
2020 N = 1012 |
||||
| Age [IQR] | 74 [69–81] | 74 [69–81] | 74 [69–80] | 0.806 | 74 [69–81] | 74 [69–79] | 74 [69–80] | 0.502 | 74 [69–81] | 74 [70–81] | 74 [70–81] | 0.153 |
| Age, years | 0.787 | 0.234 | 0.502 | |||||||||
| 65–69 (%) | 257 (26.8) | 227 (25.5) | 239 (26.2) | 186 (28.6) | 178 (27.6) | 103 (27.6) | 341 (27.4) | 287 (24.1) | 239 (23.6) | |||
| 70–74 (%) | 229 (23.9) | 235 (26.4) | 251 (27.5) | 156 (24.0) | 164 (25.4) | 95 (25.5) | 319 (25.6) | 327 (27.4) | 277 (27.4) | |||
| 75–79 (%) | 186 (19.4) | 170 (19.1) | 163 (17.8) | 127 (19.5) | 142 (22.0) | 74 (19.8) | 234 (18.8) | 220 (18.5) | 189 (18.7) | |||
| 80–84 (%) | 142 (14.8) | 137 (15.4) | 135 (14.8) | 86 (13.2) | 92 (14.3) | 40 (10.7) | 169 (13.6) | 163 (13.7) | 154 (15.2) | |||
| ≥85 (%) | 146 (15.2) | 120 (13.5) | 126 (13.8) | 95 (14.6) | 69 (10.7) | 61 (16.4) | 184 (14.8) | 195 (16.4) | 153 (15.1) | |||
| Sex | 0.081 | 0.645 | 0.869 | |||||||||
| Male (%) | 601 (62.6) | 519 (58.4) | 576 (63.0) | 399 (61.4) | 403 (62.5) | 222 (59.5) | 740 (59.3) | 719 (60.3) | 609 (60.2) | |||
| Female (%) | 359 (37.4) | 370 (41.6) | 338 (37.0) | 251 (38.6) | 242 (37.5) | 151 (40.5) | 507 (40.7) | 473 (39.7) | 403 (39.8) | |||
| Primary tumour site | 0.502 | 0.397 | 0.587 | |||||||||
| Colon | 279 (29.1) | 249 (28.0) | 246 (26.9) | 166 (25.5) | 165 (25.6) | 96 (25.7) | 361 (29.0) | 309 (25.9) | 289 (28.6) | |||
| Rectum | 97 (10.1) | 83 (9.3) | 76 (8.3) | 57 (8.8) | 56 (8.7) | 39 (10.5) | 136 (10.9) | 132 (11.1) | 106 (10.5) | |||
| Oesophagus | 55 (5.7) | 46 (5.2) | 47 (5.1) | 33 (5.1) | 38 (5.9) | 14 (3.8) | 61 (4.9) | 65 (5.5) | 49 (4.8) | |||
| Stomach | 75 (7.8) | 71 (8.0) | 60 (6.6) | 59 (9.1) | 63 (9.8) | 27 (7.2) | 101 (8.1) | 91 (7.6) | 71 (7.0) | |||
| Pancreas | 195 (20.3) | 173 (19.5) | 205 (22.4) | 139 (21.4) | 123 (19.1) | 78 (20.9) | 256 (20.5) | 249 (20.9) | 210 (20.8) | |||
| Bile duct* | 71 (7.4) | 94 (10.6) | 84 (9.2) | 63 (9.7) | 58 (9.0) | 28 (7.5) | 123 (9.9) | 101 (8.5) | 100 (9.9) | |||
| Liver (HCC) | 151 (15.7) | 134 (15.1) | 162 (17.7) | 100 (15.4) | 108 (16.7) | 72 (19.3) | 165 (13.2) | 199 (16.7) | 139 (13.7) | |||
| Small intestine | 22 (2.3) | 20 (2.3) | 16 (1.8) | 12 (1.9) | 22 (3.4) | 6 (1.6) | 26 (2.1) | 31 (2.6) | 29 (2.9) | |||
| Anus | 15 (1.6) | 19 (2.1) | 18 (2.0) | 21 (3.2) | 12 (1.9) | 13 (3.5) | 18 (1.4) | 15 (1.3) | 19 (1.9) | |||
| Tumour stage | 0.339 | 0.203 | 0.493 | |||||||||
| Non-metastatic | 775 (80.7) | 711 (80.0) | 755 (82.6) | 524 (80.6) | 512 (79.4) | 313 (83.9) | 984 (78.9) | 957 (80.3) | 818 (80.8) | |||
| Metastatic | 185 (19.3) | 178 (20.0) | 159 (17.4) | 126 (19.4) | 133 (20.6) | 60 (16.1) | 263 (21.1) | 235 (19.7) | 194 (19.2) | |||
| Charlson Comorbidity Index | 0.871 | 0.007 | 0.700 | |||||||||
| 2 | 440 (45.8) | 428 (48.1) | 450 (49.2) | 290 (44.6) | 322 (49.9) | 176 (47.2) | 578 (46.4) | 550 (46.1) | 476 (47.0) | |||
| 3 | 51 (5.3) | 47 (5.3) | 47 (5.1) | 38 (5.8) | 30 (4.7) | 19 (5.1) | 59 (4.7) | 51 (4.3) | 58 (5.7) | |||
| 4–12 | 200 (20.8) | 174 (19.6) | 181 (19.8) | 137 (21.1) | 107 (16.6) | 96 (25.7) | 257 (20.6) | 262 (22.0) | 209 (20.7) | |||
| ≥13 | 269 (28.0) | 240 (27.0) | 236 (25.8) | 185 (28.5) | 186 (28.8) | 82 (22.0) | 353 (28.3) | 329 (27.6) | 269 (26.6) | |||
| Median Charlson Comorbidity Index | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 0.146 | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7] | 0.323 | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 3 [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13] | 0.670 |
| First treated in an emergency department | 0.029 | 0.001 | 0.093 | |||||||||
| No | 820 (85.4) | 755 (84.9) | 812 (88.8) | 541 (83.2) | 575 (89.2) | 305 (81.8) | 1044 (83.7) | 1007 (84.5) | 821 (81.1) | |||
| Yes | 140 (14.6) | 134 (15.1) | 102 (11.2) | 109 (16.8) | 70 (10.8) | 68 (18.2) | 203 (16.3) | 185 (15.5) | 191 (18.9) | |||
⁎
Intrahepatic, extrahepatic and gallbladder cancers.