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. 2021 Oct 4;53(10):1569–1588. doi: 10.1007/s00726-021-03081-w

Table 5.

one-way ANOVA results of amino acids differention between Covid-19 symptom groups and controls

Groups Amino acids Mean difference Standard error Significant test
Control—Asymptomatic Taurine 135.1018853 29.0315774 0.000
Ethanolamine – 4.7934173 1.4941180 0.014
l-2-aminobutyric acid – 5.8411087 1.1815338 0.000
l-Citrulline 9.0651947 3.2215218 0.044
Control—Midly Taurine 155.2681057 27.9181284 0.000
3-Amino isobutyric acid 0.4606745 0.1105270 0.001
l-Glutamic acid 30.8029422 6.8308506 0.000
l-2-aminobutyric acid – 5.1273491 1.1362183 0.000
Trans-4-hydroxy l-proline 1.5740143 0.3988168 0.001
l-Ornithine 30.4113460 7.9340154 0.002
Control—Moderately Taurine 97.5820400 27.6805230 0.005
l-Phenylalanine – 24.0320433 7.9034386 0.023
l-2-aminobutyric acid – 6.7597633 1.1265482 0.000
Trans-4-hydroxy l-proline 1.6011433 0.3954225 0.001
Control—Severely l-Tryptophan 20.2208290 4.5366383 0.000
Taurine 111.4777759 28.1704818 0.001
l-Phenylalanine – 35.6981480 8.2017859 0.000
3-Amino isobutyric acid 0.3308616 0.1115261 0.029
l-Glutamic acid 22.5113685 6.8925950 0.012
l-2-aminobutyric acid – 6.5445317 1.1464887 0.000
l-Threonine 41.6145475 11.6936556 0.005
l-Alanine 114.3688710 38.3935978 0.028
l-Glycin 107.0110273 26.0230237 0.001
Trans-4-hydroxy l-proline 1.5934391 0.4024217 0.001
l-Proline 109.6817028 27.2539482 0.001
l-Glutamine 123.6604996 32.7916978 0.002
l-Citrulline 12.9994424 3.1259694 0.001
l-Histidine 11.0686427 3.6138749 0.022
l-Ornithine 23.2845648 8.0057314 0.034
Asymptomatic—Midly Ethanolamine 7.4789192 1.5057819 0.000
Asymptomatic—Moderately l-Glutamic acid – 29.1704120 7.1032830 0.001
Asymptomatic—Severely l-Phenylalanine – 28.1857620 8.5741312 0.011
Ethanolamine 5.7219621 1.5181794 0.002
l-Threonine 45.5370355 12.2451712 0.003
l-Proline 112.4214428 28.5393440 0.001
l-Glutamine 111.5912056 34.3382742 0.012
l-Histidine 11.8720887 3.7843184 0.018
Midly—Moderately l-Phenylalanine – 22.6687747 7.9712805 0.041
l-Tyrosine – 16.2554906 5.4333693 0.027
l-Glutamic acid – 44.8703055 6.8308506 0.000
Ethanolamine – 4.3143418 1.4368140 0.026
l-Aspartic acid – 11.9957178 3.8453843 0.018
l-Ornithine – 25.5829760 7.9340154 0.013
Midly—Severely l-Phenylalanine – 34.3348794 8.2671799 0.001
l-Threonine 33.0731461 11.7905852 0.045
l-Proline 78.1578277 27.4798581 0.040
l-Glutamine 140.0207158 33.0635105 0.000
Moderately—Severely l-Isoleucine 18.3316869 5.9392160 0.020
l-Methionine 8.7963230 2.9723867 0.029
l-Glutamic acid 36.5787318 6.8925950 0.000
l-Threonine 42.8201809 11.6936556 0.003
l-Proline 87.8582062 27.2539482 0.013
l-Glutamine 106.8802529 32.7916978 0.012
l-Citrulline 10.1693724 3.1259694 0.012