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. 2021 Sep 12;12(19):2574–2584. doi: 10.1111/1759-7714.14141

FIGURE 3.

FIGURE 3

Treatment with gefitinib plus anlotinib synergistically promoted apoptosis of PC9/GR cells. (a, c) After treatment with gefitinib, anlotinib, and gefitinib plus anlotinib for 48 h, annexin V‐FITC/PI staining was used to determine the apoptosis rate of PC9/GR cells. (b, d) The apoptotic marker protein, cleaved‐caspase 3, was analyzed by western blot analysis. Significance levels determined by the t test are indicated (ns: not significant compared with the control group. *p < 0.05, **p < 0.01 compared with the control group. #p < 0.05, ##p < 0.01 compared with the gefitinib group)