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. 2021 Sep 25;2021:2216314. doi: 10.1155/2021/2216314

Table 1.

Characteristics of the studied insomnia-associated SNPs in both insomnia and PUD GWAS.

SNP Gene EA NA Insomnia results PUD results
BETA SE P BETA SE P
rs375216017 MEIS1 GT G 0.089574 0.015720 1.21E − 08
rs62144051 MEIS1 G A 0.096151 0.016318 3.81E − 09 0.018165 0.019416 0.35
rs62144053 MEIS1 A G 0.098931 0.016272 1.20E − 09 0.026932 0.019223 0.16
rs62144054 MEIS1 A G 0.097846 0.016237 1.68E − 09 0.026976 0.019221 0.16
rs113851554 MEIS1 T G 0.178239 0.020371 2.14E − 18 0.019566 0.025498 0.44
rs182588061 MEIS1 T G 0.228449 0.036320 3.18E − 10 0.029322 0.051821 0.57
rs139775539 MEIS1 A AC 0.186994 0.022403 7.00E − 17
rs11679120 MEIS1 A G 0.187813 0.022461 6.18E − 17 0.021005 0.027931 0.45
rs115087496 MEIS1 C G 0.177042 0.022576 4.43E − 15 0.009710 0.029911 0.73
rs549771308 MEIS1 C CT 0.090546 0.015777 9.51E − 09
rs11693221 MEIS1 T C 0.170821 0.022572 3.79E − 14 0.009066 0.028027 0.75
rs574753165 SCFD2 G A 0.394740 0.067503 4.98E − 09

PUD: peptic ulcer disease; EA/NA: effect allele/no effect allele; BETA: effect size; SE: standard error of the effect size; P: P values indicate genome-wide significance in GWAS.