Table 4.
GO Functional Enrichment Analysis Results of Overlapping Genes (OGs)
| GO | ID | Description | Gene ID | Count |
|---|---|---|---|---|
| BP | GO:0030574 | Collagen catabolic process | MMP1/MMP3/MMP7/MMP9/MMP12 | 5 |
| BP | GO:0032963 | Collagen metabolic process | MMP1/MMP3/MMP7/MMP9/MMP12/PDGFRB | 6 |
| BP | GO:0022617 | Extracellular matrix disassembly | MMP1/MMP3/MMP7/MMP9/MMP12 | 5 |
| BP | GO:0150077 | Regulation of neuroinflammatory response | MMP3/MMP9/PTGS2/LRRK2 | 4 |
| BP | GO:0150076 | Neuroinflammatory response | MMP3/MMP9/PTGS2/LRRK2 | 4 |
| BP | GO:0071492 | Cellular response to UV-A | MMP1/MMP3/MMP9 | 3 |
| BP | GO:0070141 | Response to UV-A | MMP1/MMP3/MMP9 | 3 |
| BP | GO:0030198 | Extracellular matrix organization | KDR/MMP1/MMP3/MMP7/MMP9/MMP12 | 6 |
| BP | GO:0043062 | Extracellular structure organization | KDR/MMP1/MMP3/MMP7/MMP9/MMP12 | 6 |
| BP | GO:0045229 | External encapsulating structure organization | KDR/MMP1/MMP3/MMP7/MMP9/MMP12 | 6 |
| BP | GO:0006979 | Response to oxidative stress | CD38/MMP3/MMP9/PDGFRB/PTGS2/LRRK2 | 6 |
| BP | GO:0072593 | Reactive oxygen species metabolic process | MMP3/NOS2/PDGFRB/PTGS2/LRRK2 | 5 |
| BP | GO:0010035 | Response to inorganic substance | CA2/KDR/MMP3/MMP9/PDGFRB/LRRK2 | 6 |
| BP | GO:1904645 | Response to amyloid-beta | MMP3/MMP9/MMP12 | 3 |
| BP | GO:0030335 | Positive regulation of cell migration | IGFBP5/KDR/MMP7/MMP9/PDGFRB/PLAU/PTGS2/SELP | 8 |
| BP | GO:2000147 | Positive regulation of cell motility | IGFBP5/KDR/MMP7/MMP9/PDGFRB/PLAU/PTGS2/SELP | 8 |
| BP | GO:0051272 | Positive regulation of cellular component movement | IGFBP5/KDR/MMP7/MMP9/PDGFRB/PLAU/PTGS2/SELP | 8 |
| BP | GO:0040017 | Positive regulation of locomotion | IGFBP5/KDR/MMP7/MMP9/PDGFRB/PLAU/PTGS2/SELP | 8 |
| BP | GO:0007565 | Female pregnancy | STS/CD38/IGFBP5/MMP7/MMP9 | 5 |
| BP | GO:0044706 | Multi-multicellular organism process | STS/CD38/IGFBP5/MMP7/MMP9 | 5 |
| BP | GO:0070482 | Response to oxygen levels | CD38/EDNRA/NOS2/PDGFRB/PLAU/PTGS2 | 6 |
| BP | GO:0009636 | Response to toxic substance | EPHX2/PDGFRB/PTGS2/ABCG2/AKR1B10 | 5 |
| BP | GO:0042759 | Long-chain fatty acid biosynthetic process | EPHX2/FADS1/PTGS2 | 3 |
| BP | GO:0050801 | Ion homeostasis | CA2/CD38/EDNRA/CXCR1/KDR/ABCG2/LRRK2 | 7 |
| BP | GO:0019932 | Second-messenger-mediated signaling | CXCR1/KDR/NOS2/SELP/LRRK2 | 5 |
| CC | GO:0030667 | Secretory granule membrane | CD38/CXCR1/PLAU/SELL/SELP | 5 |
| MF | GO:0004222 | Metalloendopeptidase activity | MMP1/MMP3/MMP7/MMP9/MMP12 | 5 |
| MF | GO:0004252 | Serine-type endopeptidase activity | MMP1/MMP3/MMP7/MMP9/PLAU | 5 |
| MF | GO:0008236 | Serine-type peptidase activity | MMP1/MMP3/MMP7/MMP9/PLAU | 5 |
| MF | GO:0008237 | Metallopeptidase activity | MMP1/MMP3/MMP7/MMP9/MMP12 | 5 |
| MF | GO:0017171 | Serine hydrolase activity | MMP1/MMP3/MMP7/MMP9/PLAU | 5 |
| MF | GO:0004175 | Endopeptidase activity | MMP1/MMP3/MMP7/MMP9/MMP12/PLAU | 6 |
| MF | GO:0016788 | Hydrolase activity, acting on ester bonds | STS/CA2/CDC25B/EDNRA/EPHX2/PFKFB3/LRRK2 | 7 |