Table 2.
Characteristic | Total | TyG Index | P value | |
---|---|---|---|---|
Low (<8.49) | High (≥8.49) | |||
No. (%) | No. (%) | No. (%) | ||
Total patients | 14,158 | 7080 (50.0) | 7078 (50.0) | |
Gender | <0.001 | |||
Male | 6801 (48.0) | 3047 (43.0) | 3754 (53.0) | |
Female | 7357 (52.0) | 4033 (57.0) | 3324 (47.0) | |
Age | <0.001 | |||
20–39 years | 4608 (32.5) | 2906 (41.0) | 1702 (24.0) | |
40–59 years | 4744 (33.5) | 2206 (31.2) | 2538 (35.9) | |
60+ years | 4806 (33.9) | 1968 (27.8) | 2838 (40.1) | |
Race | <0.001 | |||
Non-Hispanic white | 5833 (41.2) | 2790 (39.4) | 3043 (43.0) | |
Non-Hispanic black | 2847 (20.1) | 1875 (26.5) | 972 (13.7) | |
Mexican American | 2165 (15.3) | 847 (12.0) | 1318 (18.6) | |
Other Hispanic | 1562 (11.0) | 672 (9.5) | 890 (12.6) | |
Other | 1751 (12.4) | 896 (12.7) | 855 (12.1) | |
Education | <0.001 | |||
Less than high school | 3516 (24.8) | 1456 (20.6) | 2060 (29.1) | |
High school or equivalent | 3192 (22.5) | 1549 (21.9) | 1643 (23.2) | |
College or above | 7440 (52.5) | 4073 (57.5) | 3367 (47.6) | |
Other | 10 (0.1) | 2 (0.0) | 8 (0.1) | |
Marital status | <0.001 | |||
Married | 7358 (52.0) | 3417 (48.3) | 3941 (55.7) | |
Unmarried/Other | 6800 (48.0) | 3663 (51.7) | 3137 (44.3) | |
BMI (kg/m2) | 29.10, 6.91 | 27.50, 6.69 | 30.70, 6.76 | <0.001 |
Hypertension | <0.001 | |||
Yes | 5148 (36.4) | 2010 (28.4) | 3138 (44.3) | |
No/Unknown | 9010 (63.6) | 5070 (71.6) | 3940 (55.7) | |
Diabetes | <0.001 | |||
Yes | 1836 (13.0) | 386 (5.5) | 1450 (20.5) | |
Prediabetes | 11,974 (84.6) | 6563 (92.7) | 5411 (76.4) | |
No/Unknown | 348 (2.5) | 131 (1.9) | 217 (3.1) | |
Vigorous recreational activities | <0.001 | |||
Yes | 3030 (15.0) | 1914 (27.0) | 1116 (15.8) | |
No | 11,128 (78.6) | 5166 (73.0) | 5962 (84.2) | |
Moderate recreational activities | <0.001 | |||
Yes | 5654 (39.9) | 3079 (43.5) | 2575 (36.4) | |
No | 8504 (60.1) | 4001 (56.4) | 4503 (63.6) | |
Kidney stone | <0.001 | |||
Yes | 1346 (9.5) | 523 (7.4) | 823 (11.6) | |
No | 12,812 (90.5) | 6557 (92.6) | 6255 (88.4) | |
HOMA-IR | 4.72, 8.59 | 2.44, 3.04 | 5.59, 8.84 | <0.001 |
Blood urea nitrogen | 13.64, 5.87 | 13.11, 5.39 | 14.17, 6.27 | <0.001 |
Creatinine | 0.88, 0.38 | 0.86, 0.35 | 0.90, 0.41 | <0.001 |
Uric acid | 5.49, 1.44 | 5.14, 1.34 | 5.83, 1.45 | <0.001 |
Fasting glucose | 102.93, 34.07 | 91.68, 12.68 | 114.17, 43.68 | <0.001 |
TC | 190.89, 40.60 | 181.38, 36.93 | 200.40, 41.86 | <0.001 |
TG | 116.29, 65.46 | 70.03, 21.37 | 162.56, 61.91 | <0.001 |
HDL-C | 54.26, 15.95 | 60.31, 16.43 | 48.21, 12.86 | <0.001 |
LDL-C | 113.37, 35.49 | 107.07, 32.04 | 119.67, 37.59 | <0.001 |
TyG | 8.52, 0.64 | 8.01, 0.35 | 9.02, 0.42 | <0.001 |
Urine creatinine | 125.76, 77.00 | 126.66, 79.97 | 124.86, 73.90 | 0.163 |
Notes: For categorical variables, P values were analyzed by chi-square tests; For continuous variables, the t-test for slope was used in generalized linear models; All the continuous variables were recorded by mean ± standard deviation (SD).
Abbreviations: PSM, propensity score matching; BMI, body mass index; HOMA-IR, homeostasis model assessment for IR; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TyG, triglyceride–glucose.